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Delivering Innovative Therapies for Patients<br>Accelerating the Transition from

Delivering Innovative Therapies for Patients
Accelerating the Transition from "New in China" to "New Globally"

Guided by its vision to "be a leading global pharmaceutical company by delivering innovative therapies for patients", Sino Biopharm has consistently strengthened its R&D investment and refined its innovation ecosystem. The company has established a leading domestic drug discovery platform with core competitive advantages in four key therapeutic areas: oncology, hepatology, respiratory diseases, and surgery/analgesia. Its R&D pipeline encompasses multiple cutting-edge therapeutic targets. Sino Biopharm ranks among the top 3 in innovation capability in China. According to Citeline's 2024 rankings, R&D pipeline size ranking second domestically and 15th globally.

The company has established multiple R&D and innovation centers in Beijing, Nanjing, Shanghai, as well as across Asia, Europe, and North America, supporting a global R&D team of over 2,800 professionals. Committed to an open and mutually beneficial collaboration model, Sino Biopharm strives to become a world-leading pharmaceutical enterprise. Through independent innovation, strategic business development (BD) partnerships, international collaborations, and the establishment of advanced technology platforms, the company has forged extensive and deep partnerships with renowned research institutions and academic organizations worldwide. These efforts have enabled Sino Biopharm to effectively harness global innovation resources and enhance its international presence.
  • 0 %+
    R&D Personnel Hold a Master's Degree or Higher
  • 0 +
    Innovative drug projects in the pipeline
  • 0 +
    National Science and Technology Major Projects for
    "Innovative Drug Research and Development" undertaken
  • 0 +
    Patents Granted Cumulatively

TECHNOLOGY INNOVATION

RESEARCHING PIPELINE

100

All

9

Preclinical

22

Phase I

21

Phase II

23

Phase III/Pivotal Clinical

25

Marketing Application
Product Area
  • Oncology
  • Respiratory
  • Hepatology
    Metabolism
  • Surgery
    Analgesic
Drug Type
  • Innovative Drug
  • Biosimilar
    Generic Drug
Development Phase
  • Phase I
  • Phase II
  • Phase III
  • Marketing Application
Development Phase
  • BE Study
  • Phase I
  • Pivotal Clinical
  • Marketing Application
Product Target/Mechanism of Action Drug Type Indication IIIIIIMarketing Application
TQB3616 CDK2/4/6 inhibitor Small molecule HR+/HER2- breast cancer
TQ05105 JAK/ROCK inhibitor Small molecule Myelofibrosis, graft versus host disease, hemophagocytic syndrome
AL2846 AXL/MET tyrosine kinase inhibitor Small molecule Non-small cell lung cancer, differentiated thyroid cancer
TQB3454 IDH1 inhibitor Small molecule Advanced biliary tract cancer with IDH1 mutation
TQB2102 HER2 bispecific ADC Large molecule Breast cancer, non-small cell lung cancer, biliary tract cancer, colorectal cancer, gastric cancer, and other advanced malignant neoplasm
M701 CD3/EpCAM bispecific antibody Large molecule Malignant ascites, malignant pleural effusion
TQB3473 SYK inhibitor Small molecule Primary immune thrombocytopenia
FHND9041 EGFR inhibitor (3rd generation) Small molecule Non-small cell lung cancer
TQB3909 BCL-2 inhibitor Small molecule Chronic lymphocytic leukaemia/small lymphocytic lymphoma, acute myeloid leukaemia, acute lymphocytic leukaemia, etc.
LM-108 CCR8 monoclonal antibody Large molecule Advanced malignant neoplasm
TQB2868 Anti-PD-1/TGF-β bifunctional fusion protein Large molecule Pancreas cancer
TQB2930 HER2 bispecific antibody Large molecule Breast cancer, gastric cancer
TQB2916 CD40 agonistic monoclonal antibody Large molecule Advanced malignant neoplasm
TQB2928 CD47 monoclonal antibody Large molecule Bone sarcoma
TQB3702 BTK inhibitor Small molecule Relapsed/refractory advanced hematologic malignancies
TQB3617 BET inhibitor Small molecule Myelofibrosis
TQB3915 Selective estrogen receptor covalent antagonist (SERCA) Small molecule HR+/HER2- breast cancer
TQB2825 CD20/CD3 bispecific antibody Large molecule Follicular lymphoma, diffuse large B-cell lymphoma, mantle cell lymphoma
FHND6091 Proteasome inhibitor Small molecule Multiple myeloma, biliary tract cancer, lupus erythematosus
FHND5071 RET inhibitor Small molecule Solid tumor
NTQ1062 AKT inhibitor Small molecule Solid tumor
TQB3720 Androgen receptor (AR) antagonist Small molecule Prostate cancer
TQB2103 Claudin18.2 ADC Large molecule Advanced malignant neoplasm
TQB2934 BCMA/CD3 bispecific antibody Large molecule Multiple myeloma
TQB3912 AKT inhibitor Small molecule Advanced malignant neoplasm
TQB2922 EGFR/cMET bispecific antibody Large molecule Advanced malignant neoplasm
TQB3006 SOS1 inhibitor Small molecule Advanced malignant neoplasm
TQB3107 XPO1 inhibitor Small molecule Lymphoma, leukaemia, and various solid tumors
TQB3117 ATM inhibitor Small molecule Advanced malignant neoplasm
TQB3911 BCR-ABL1 tyrosine kinase inhibitor Small molecule Hematological malignancy
TQB3002 EGFR inhibitor (4th generation) Small molecule Advanced malignant neoplasm
TQB2029 GPRC5D/CD3 bispecific antibody Large molecule Multiple myeloma
TQB2252 PD-1/LAG-3 combination Large molecule Advanced malignant neoplasm
TCC1727 Selective ATR inhibitor Small molecule Advanced malignant neoplasm
NTQ3617 MAT2A inhibitor Small molecule Advanced malignant neoplasm
TQH2722 IL-4Rα monoclonal antibody Large molecule Chronic sinusitis with/without nasal polyps, atopic dermatitis, seasonal allergic rhinitis
TQC2731 TSLP monoclonal antibody Large molecule Severe asthma, chronic sinusitis with nasal polyps, chronic obstructive pulmonary disease (COPD)
TQC3721 PDE3/4 inhibitor Small molecule Chronic obstructive pulmonary disease (COPD)
TQC2938 ST2 monoclonal antibody Large molecule Asthma, chronic obstructive pulmonary disease (COPD)
TDI01 ROCK2 inhibitor Small molecule Idiopathic pulmonary fibrosis (IPF), graft-versus-host disease (GVHD)
CPX102 Type III interferon (IL-29) Large molecule Respiratory syncytial virus (RSV) infection
TCR1672 P2X3 antagonist Small molecule Refractory chronic cough
TQC3927 MABA dual target Small molecule Chronic obstructive pulmonary disease (COPD)
TQD3524 Polymyxin E2 Small molecule Carbapenem-resistant organism (CRO) infection
TQD3606 Meropenem and avibactam sodium Small molecule Carbapenem-resistant organism (CRO) infection
TQC3301 Budesonide inhalation spray Small molecule Asthma
Lanifibranor Pan-PPAR agonist Small molecule Metabolic dysfunction-associated steatohepatitis (MASH)
TQA2225 FGF21 fusion protein Large molecule Metabolic dysfunction-associated steatohepatitis (MASH)
TQ-A3334 TLR-7 agonist Small molecule Hepatitis B
TQA3810 TLR-8 agonist Small molecule Hepatitis B
TQA3605 HBV capsid assembly modulator (CAM) Small molecule Hepatitis B
TQA3038 siRNA Small molecule Hepatitis B
CPX101 GIPR antagonist/GLP-1R agonist Large molecule Weight loss
PL-5 Antimicrobial peptide Category 1 new drug Secondary wound infection
QP001 Meloxicam injection (COX-2 inhibitor) Category 2 new drug Postoperative analgesia in adults
Naldemedine Peripherally acting μ-opioid receptor antagonist Category 1 new drug Opioid-induced constipation
TRD205 AT2R antagonist Category 1 new drug Neuropathic pain
TRD303 Ropivacaine extended-release solution (local anesthetic) Category 2 new drug Postoperative analgesia
YMP Dexmedetomidine transdermal patch (α2-adrenergic receptor agonist) Category 2 new drug Perioperative insomnia
Product Indication BE StudyPhase IPivotal ClinicalMarketing Application
Degarelix acetate for injection Advanced prostate cancer
Enzalutamide soft capsules Prostate cancer
Ruxolitinib tablets Myelofibrosis
Ibrutinib capsules Mantle cell lymphoma, chronic lymphocytic leukaemia, etc.
Pamidronate disodium injection Neoplasm bone metastasis
Apalutamide tablets Prostate cancer
Nelarabine injection Lymphocytic leukaemia, lymphoma
Abiraterone acetate tablets (II) Prostate cancer
Daratumumab injection Multiple myeloma
Netupitant and palonosetron capsules Chemotherapy-induced vomiting
Ixazomib citrate capsules Multiple myeloma
Relugolix tablets Prostate cancer
Chidamide tablets Breast cancer, diffuse large B-cell lymphoma, etc.
Tedizolid phosphate for injection Antibacterial
Umeclidinium and vilanterol inhalation powder Chronic obstructive pulmonary disease (COPD)
Tiotropium bromide inhalation powder Chronic obstructive pulmonary disease (COPD)
Amphotericin B liposome for injection Deep fungal infection
Posaconazole injection Antifungal
Procaterol hydrochloride granules Bronchodilator
Arformoterol tartrate solution for nebulization Chronic obstructive pulmonary disease (COPD)
Bromhexine hydrochloride solution for inhalation Patients with difficulty expectorating sputum due to chronic bronchitis, asthma, etc.
Mepolizumab injection Asthma, chronic sinusitis with nasal polyps
Delamanid tablets Multidrug-resistant pulmonary tuberculosis
Fluticasone furoate and vilanterol inhalation powder Asthma, chronic obstructive pulmonary disease (COPD)
Salmeterol and fluticasone inhalation powder Asthma
Beraprost sodium sustained-release tablets Primary pulmonary arterial hypertension, pulmonary arterial hypertension complicated by scleroderma
Obeticholic acid tablets Primary biliary cholangitis
Saxagliptin and metformin hydrochloride extended-release tablets Type 2 diabetes mellitus
Empagliflozin and metformin hydrochloride extended-release tablets Type 2 diabetes mellitus
Insulin degludec injection Type 2 diabetes mellitus
Semaglutide injection Type 2 diabetes mellitus, weight loss
Insulin degludec and liraglutide injection Type 2 diabetes mellitus
Empagliflozin, linagliptin, and metformin hydrochloride extended-release tablets Type 2 diabetes mellitus
Recombinant human coagulation factor VIIa for injection Hemorrhagic disorder
Eldecalcitol soft capsules Osteoporosis
Flurbiprofen patch (2nd generation) Analgesia and anti-inflammation for the following diseases and symptoms: osteoarthritis, scapulohumeral periarthritis, myalgia, swelling and pain due to trauma, etc.
Mirogabalin tablets Neuralgia
Methocarbamol injection Adjunctive therapy for acute musculoskeletal pain or discomfort
Risedronate sodium tablets Treatment and prevention of osteoporosis in postmenopausal women
Pregabalin extended-release tablets Diabetic peripheral neuropathic pain (DPNP)
Elagolix sodium tablets Endometriosis related pain
No data available